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Merck
CN

P9130

Pyridoxal hydrochloride

≥99% (HPLC)

Synonym(s):

3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde hydrochloride, PL HCl

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About This Item

Empirical Formula (Hill Notation):
C8H9NO3 · HCl
CAS Number:
65-22-5
Molecular Weight:
203.62
Beilstein:
3656994
EC Number:
200-602-5
MDL number:
MFCD00012809
UNSPSC Code:
12352205
PubChem Substance ID:
24899009
NACRES:
NA.79

Key Documents

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biological source

synthetic (organic)

Quality Level

200

Assay

≥99% (HPLC)

form

powder

technique(s)

HPLC: suitable

color

white to off-white

mp

173 °C (dec.) (lit.)

storage temp.

−20°C

SMILES string

Cl[H].[H]C(=O)c1c(CO)cnc(C)c1O

InChI

1S/C8H9NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,4,10,12H,3H2,1H3;1H

InChI key

FCHXJFJNDJXENQ-UHFFFAOYSA-N

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Application

For the labeling of amino acids and their detection in picomolar amounts; Coenzymes and Cofactors, vol. 1: Vitamin B6, Pyridoxal Phosphate
Pyridoxal hydrochloride has been used as a calibrant for liquid chromatography of food samples. It has also been used as a component of arginine decarboxylase broth and lysine decarboxylase broth (LDB) for culturing lactic acid bacteria (LAB) and food-borne pathogens (FBP), respectively.

Biochem/physiol Actions

Pyridoxal hydrochloride interacts with cysteine of cathepsins and inhibits their activity. It elicits protective function in cornu Ammonis (CA) 1 neurons during ischemia.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF7563V
0000503015
0000503015
0000477995
0000477995

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Neuroprotective effects of pyridoxal phosphate and pyridoxal against ischemia in monkeys
Yamashima T, et al.
Nutritional Neuroscience, 4(5), 389-397 (2001)
Certification of B-group vitamins (B1, B2, B6, and B12) in four food reference materials
Ollilainen V, et al.
Journal of Agricultural and Food Chemistry, 49(1), 315-321 (2001)
The function of lactic acid bacteria on biogenic amines production by food-borne pathogens in arginine decarboxylase broth
Ozogul F, et al.
Food Science and Technology Research, 18(6), 795-804 (2012)
Effects of forage family on apparent ruminal synthesis of B vitamins in lactating dairy cows
Castagnino DS, et al.
Journal of Dairy Science, 99(3), 1884-1894 (2016)
Masoud Vedadi et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(43), 15835-15840 (2006-10-13)
The 3D structures of human therapeutic targets are enabling for drug discovery. However, their purification and crystallization remain rate determining. In individual cases, ligands have been used to increase the success rate of protein purification and crystallization, but the broad
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Articles

Vitamin B6, Pyridoxal and Pyridoxine in Cell Culture

Vitamin B6's impact on serum-free cell culture systems is explored for protein manufacturing.

细胞培养中的维生素B6、吡哆醛和吡哆醇

该页面针对维生素B6、吡哆醛和吡哆醇如何影响无血清、无蛋白细胞培养系统（用于包括单克隆抗体在内的异源蛋白的生物制造）的性能提供了全面的分析。本页介绍吡哆醛、吡哆醇的体外化学和生物化学。

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