P9158
Pyridoxamine dihydrochloride
BioReagent, suitable for cell culture
Synonym(s):
4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochloride
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About This Item
Empirical Formula (Hill Notation):
C8H12N2O2 · 2HCl
CAS Number:
Molecular Weight:
241.11
UNSPSC Code:
12352205
NACRES:
NA.75
PubChem Substance ID:
EC Number:
208-357-6
Beilstein/REAXYS Number:
3632748
MDL number:
biological source
synthetic (organic)
Quality Segment
product line
BioReagent
assay
≥98%
form
powder
mol wt
Mw 241.11 g/mol
technique(s)
cell culture | mammalian: suitable
color
white to off-white
mp
224-226 °C (dec.) (lit.)
solubility
water: soluble 50 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
SMILES string
Cl[H].Cl[H].Cc1ncc(CO)c(CN)c1O
InChI
1S/C8H12N2O2.2ClH/c1-5-8(12)7(2-9)6(4-11)3-10-5;;/h3,11-12H,2,4,9H2,1H3;2*1H
InChI key
HNWCOANXZNKMLR-UHFFFAOYSA-N
Application
Use in mammalian cell culture as an alternative to pyridoxine or pyridoxal. Vitamin B6 is a required component of cell culture media. Historically, media have been supplemented with vitamin B6 in the aldehyde form, pyridoxal. While this is a biologically active form of vitamin B6, it is unstable in liquid media. When cells are able to utilize either pyridoxine and/or pyridoxamine, they are preferred supplement versus pyridoxal. A number of classical media are now offered with a choice between pyridoxal and pyridoxine as the vitamin A source.
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Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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