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Merck
CN

P9511

3-sn-Phosphatidic acid sodium salt from egg yolk lecithin

≥98%, Phosphatidic acid precursor, powder

Synonym(s):

1,2-Diacyl-sn-glycero-3-phosphate sodium salt, L-α-Phosphatidic acid sodium salt, PA

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About This Item

UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98%
Form:
powder
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Product Name

3-sn-Phosphatidic acid sodium salt from egg yolk lecithin, ≥98%

Quality Segment

assay

≥98%

form

powder

storage temp.

−20°C

SMILES string

[Na+].[Na+].OC[C@@H](O)COP([O-])([O-])=O

InChI

1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;/q;2*+1/p-2/t3-;;/m1../s1

InChI key

GEKBIENFFVFKRG-HWYNEVGZSA-L

General description

Phosphatidic acid is obtained from phosphatidylcholine with the help of phospholipase D.

Application

3-sn-Phosphatidic acid sodium salt from egg yolk lecithin
  • in the reaction mixture for CDS (cytidine triphosphate:phosphatidate cytidyltransferase) assay and reference lipid for thin layer chromatography (TLC)
  • as a standard to compare the generated radiolabeled phosphatidic acid (PA)
  • to examine its effects on At-Rac2–associated kinase activity

Biochem/physiol Actions

Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol, phosphatidic acid and lysophosphatidic acid.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphodiesterases, Phosphoinositide Kinases and Phosphoprotein Phosphatases (Serine/Threonine) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

Prepared from L-α-phosphatidylcholine by hydrolysis with cabbage phospholipase D.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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