P9528
Polyuridylic acid potassium salt
Synonym(s):
Poly(U) potassium salt
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Assay:
≥98% (TLC)
Form:
lyophilized powder
Solubility:
water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless
Storage temp.:
−20°C
assay
≥98% (TLC)
Quality Level
form
lyophilized powder
solubility
water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless
storage temp.
−20°C
SMILES string
[P](=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)[n]2[c]([nH][c](cc2)=O)=O)(O)O
InChI
1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChI key
DJJCXFVJDGTHFX-XVFCMESISA-N
Application
Polyuridylic acid (Poly(U)), a homopolymer of uridine, is used as a single-stranded RNA model compound often in comparison with other ssRNA model oligonucleotides such as Poly(I) and Poly(C) to study processes that are dependent upon ssRNA regulation such as Toll-like receptor regulation. Poly(U) is used as an effective agonist for TLR7.
Preparation Note
Prepared from UDP using polynucleotide phosphorylase.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Tiago Antonio de Souza et al.
PloS one, 7(2), e32305-e32305 (2012-03-03)
Plant pathogenic bacteria utilize an array of effector proteins to cause disease. Among them, transcriptional activator-like (TAL) effectors are unusual in the sense that they modulate transcription in the host. Although target genes and DNA specificity of TAL effectors have
Soren Nielsen et al.
Science (New York, N.Y.), 340(6140), 1577-1580 (2013-07-03)
Gene expression in organisms involves many factors and is tightly controlled. Although much is known about the initial phase of transcription by RNA polymerase III (Pol III), the enzyme that synthesizes the majority of RNA molecules in eukaryotic cells, termination
Liam M Longo et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(27), 15731-15739 (2020-06-21)
De novo emergence demands a transition from disordered polypeptides into structured proteins with well-defined functions. However, can polypeptides confer functions of evolutionary relevance, and how might such polypeptides evolve into modern proteins? The earliest proteins present an even greater challenge
A Maxwell Burroughs et al.
Nucleic acids research, 40(4), 1424-1437 (2011-11-08)
Recent research hints at an underappreciated complexity in pre-miRNA processing and regulation. Global profiling of pre-miRNA and its potential to increase understanding of the pre-miRNA landscape is impeded by overlap with highly expressed classes of other non coding (nc) RNA.
Yann Fichou et al.
Frontiers in neuroscience, 13, 1339-1339 (2020-01-11)
The aggregation of the human tau protein into neurofibrillary tangles is directly diagnostic of many neurodegenerative conditions termed tauopathies. The species, factors and events that are responsible for the initiation and propagation of tau aggregation are not clearly established, even
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P9528-100MG | 04061834403555 |
| P9528-10MG | 04061833289990 |
| P9528-25MG | 04061833290002 |
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service