P9528
Polyuridylic acid potassium salt
Synonym(s):
Poly(U) potassium salt
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About This Item
Assay:
≥98% (TLC)
Form:
lyophilized powder
Solubility:
water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless
Storage temp.:
−20°C
assay
≥98% (TLC)
Quality Segment
form
lyophilized powder
solubility
water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless
storage temp.
−20°C
SMILES string
[P](=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)[n]2[c]([nH][c](cc2)=O)=O)(O)O
InChI
1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChI key
DJJCXFVJDGTHFX-XVFCMESISA-N
Application
Polyuridylic acid (Poly(U)), a homopolymer of uridine, is used as a single-stranded RNA model compound often in comparison with other ssRNA model oligonucleotides such as Poly(I) and Poly(C) to study processes that are dependent upon ssRNA regulation such as Toll-like receptor regulation. Poly(U) is used as an effective agonist for TLR7.
Preparation Note
Prepared from UDP using polynucleotide phosphorylase.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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