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Merck
CN

P9528

Polyuridylic acid potassium salt

Synonym(s):

Poly(U) potassium salt

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About This Item

CAS Number:
UNSPSC Code:
41106305
NACRES:
NA.51
MDL number:
Assay:
≥98% (TLC)
Form:
lyophilized powder
Solubility:
water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless
Storage temp.:
−20°C
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assay

≥98% (TLC)

Quality Segment

form

lyophilized powder

solubility

water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless

storage temp.

−20°C

SMILES string

[P](=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)[n]2[c]([nH][c](cc2)=O)=O)(O)O

InChI

1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

InChI key

DJJCXFVJDGTHFX-XVFCMESISA-N

Application

Polyuridylic acid (Poly(U)), a homopolymer of uridine, is used as a single-stranded RNA model compound often in comparison with other ssRNA model oligonucleotides such as Poly(I) and Poly(C) to study processes that are dependent upon ssRNA regulation such as Toll-like receptor regulation. Poly(U) is used as an effective agonist for TLR7.

Preparation Note

Prepared from UDP using polynucleotide phosphorylase.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Product Information Sheet






Global Trade Item Number

SKUGTIN
P9528-100MG04061834403555
P9528-10MG04061833289990
P9528-25MG04061833290002