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Merck
CN

P9547

Prilocaine hydrochloride

≥98% (TLC)

Synonym(s):

N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C13H20N2O · HCl
CAS Number:
Molecular Weight:
256.77
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
217-244-0
MDL number:
Assay:
≥98% (TLC)
Form:
powder
Quality level:
Technical Service
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Quality Level

assay

≥98% (TLC)

form

powder

originator

AstraZeneca

SMILES string

Cl[H].CCCNC(C)C(=O)Nc1ccccc1C

InChI

1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H

InChI key

BJPJNTKRKALCPP-UHFFFAOYSA-N

Biochem/physiol Actions

Used for local nerve block and for spinal anesthesia; pharmacological properties are similar to those of lidocaine.

Features and Benefits

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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K Nakamura et al.
Canadian journal of anaesthesia = Journal canadien d'anesthesie, 46(5 Pt 1), 476-482 (1999-06-01)
To determine whether prilocaine, a local anesthetic, induces apoptosis in osteoblastic cells. After reaching subconfluence, human osteoblastic Saos-2 and MG63 cells and mouse osteoblastic MC3T3-E1 cells were exposed for 48 hr to varying concentrations of prilocaine up to 10 mM
S Schreiber et al.
European journal of pediatrics, 172(2), 265-268 (2012-10-25)
Venipuncture and intravenous cannulation are the most common painful procedures performed on children. The most widely used topical anesthetic is eutectic mixture of local anesthetics (EMLA). EMLA use is associated with a transient cutaneous vasoconstriction which can make it difficult
Young-Eun Moon et al.
Archives of physical medicine and rehabilitation, 94(5), 919-924 (2012-12-25)
To compare the effects of a vapocoolant spray and an eutectic mixture of local anesthetics (EMLA) cream in reducing pain during needle electromyography examination. Randomized controlled trial. Physical medicine and rehabilitation department of a university hospital. Adults who underwent needle



Global Trade Item Number

SKUGTIN
P9547-5G04061834403807
P9547-10G04061834403777
P9547-1G04061834403784