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Pristane

synthetic, liquid, sterile-filtered, BioReagent

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Synonym(s):
2,6,10,14-Tetramethylpentadecane
Linear Formula:
(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)(CH2)3CH(CH3)2
CAS Number:
1921-70-6
Molecular Weight:
268.52
Beilstein:
1720538
EC Number:
217-650-8
MDL number:
MFCD00008952
PubChem Substance ID:
24899044
NACRES:
NA.75

biological source

synthetic

sterility

sterile-filtered

product line

BioReagent

Assay

≥95%

form

liquid

impurities

endotoxin, tested

refractive index

n20/D 1.438 (lit.)

bp

68 °C/0.001 mmHg (lit.)

density

0.783 g/mL at 20 °C (lit.)

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC(C)C

InChI

1S/C19H40/c1-16(2)10-7-12-18(5)14-9-15-19(6)13-8-11-17(3)4/h16-19H,7-15H2,1-6H3

InChI key

XOJVVFBFDXDTEG-UHFFFAOYSA-N

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General description

Pristane is a natural saturated terpenoid alkane used in research on the pathogenesis of autoimmune diseases such as arthritis and lupus.

Application

Used to induce disease models for study including arthritis as a non-antigenic arthritogenic adjuvant and plasmacytomas.

Packaging

Packaged in flame sealed ampules.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315 - H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

> 110 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Chen Liu et al.
Journal of autoimmunity, 113, 102498-102498 (2020-06-17)
E proteins, a subset of basic helix-loop-helix (bHLH) proteins, are transcription activators and their functions are inhibited by DNA-binding inhibitor (Id) 1-4. Studies have shown that Treg levels are decreased in Id3 knockout mice. Mice over-expressing Id1 in CD4 T
Sae Won Kim et al.
Oncotarget, 5(5), 1226-1240 (2014-04-10)
Identification of novel biomarkers for tumor-initiating cells (TICs) is of critical importance for developing diagnostic and therapeutic strategies against cancers. Here we identified the role of KIAA1114, a full-length translational product of the trophinin gene, as a distinctive marker for
D A C Botte et al.
Clinical and experimental immunology, 177(2), 381-390 (2014-03-29)
Alpha-melanocyte stimulating hormone (α-MSH) is a neuropeptide exhibiting anti-inflammatory activity in experimental models of autoimmune diseases. However, no studies thus far have examined the effects of α-MSH on systemic lupus erythematosus (SLE). This study aimed to determine the effects of
Nicholas C Van de Velde et al.
Immunology letters, 130(1-2), 82-88 (2009-12-17)
The major human Fc receptor, huFcgammaRIIa, is implicated in the development of autoimmune arthritis in humans but until recently has not been studied in mouse models. We evaluated potential roles of FcgammaRIIa by using transgenic mice expressing the receptor. We
Yiqin Shi et al.
Journal of immunology (Baltimore, Md. : 1950), 193(10), 5129-5139 (2014-10-05)
Diffuse pulmonary hemorrhage (DPH) is an uncommon but critical complication of systemic lupus erythematosus. Peritoneal administration of 2,6,10,14-tetramethylpentadecane (pristane) can recapitulate a lupus-like syndrome in mice, which can develop into DPH within a few weeks, especially in C57BL/6 mice. Mac-1
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