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Merck
CN

P9622

Pristane

synthetic, liquid, sterile-filtered, BioReagent

Synonym(s):

2,6,10,14-Tetramethylpentadecane

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About This Item

Linear Formula:
(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)(CH2)3CH(CH3)2
CAS Number:
1921-70-6
Molecular Weight:
268.52
UNSPSC Code:
41116107
NACRES:
NA.75
PubChem Substance ID:
24899044
EC Number:
217-650-8
Beilstein/REAXYS Number:
1720538
MDL number:
MFCD00008952

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InChI

1S/C19H40/c1-16(2)10-7-12-18(5)14-9-15-19(6)13-8-11-17(3)4/h16-19H,7-15H2,1-6H3

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC(C)C

InChI key

XOJVVFBFDXDTEG-UHFFFAOYSA-N

biological source

synthetic

sterility

sterile-filtered

product line

BioReagent

assay

≥95%

form

liquid

impurities

endotoxin, tested

Quality Level

200

bp

68 °C/0.001 mmHg (lit.)

density

0.783 g/mL at 20 °C (lit.)

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General description

Pristane is a natural saturated terpenoid alkane used in research on the pathogenesis of autoimmune diseases such as arthritis and lupus.

Application

Used to induce disease models for study including arthritis as a non-antigenic arthritogenic adjuvant and plasmacytomas.

Packaging

Packaged in flame sealed ampules.

hcodes

H315,H319

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

>230.0 °F - closed cup

flash_point_c

> 110 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
RNBJ7338
RNBJ2609
RNBH8347
RNBG7123
RNBF1748

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Chen Liu et al.
Journal of autoimmunity, 113, 102498-102498 (2020-06-17)
E proteins, a subset of basic helix-loop-helix (bHLH) proteins, are transcription activators and their functions are inhibited by DNA-binding inhibitor (Id) 1-4. Studies have shown that Treg levels are decreased in Id3 knockout mice. Mice over-expressing Id1 in CD4 T
Nicholas C Van de Velde et al.
Immunology letters, 130(1-2), 82-88 (2009-12-17)
The major human Fc receptor, huFcgammaRIIa, is implicated in the development of autoimmune arthritis in humans but until recently has not been studied in mouse models. We evaluated potential roles of FcgammaRIIa by using transgenic mice expressing the receptor. We
Yiqin Shi et al.
Journal of immunology (Baltimore, Md. : 1950), 193(10), 5129-5139 (2014-10-05)
Diffuse pulmonary hemorrhage (DPH) is an uncommon but critical complication of systemic lupus erythematosus. Peritoneal administration of 2,6,10,14-tetramethylpentadecane (pristane) can recapitulate a lupus-like syndrome in mice, which can develop into DPH within a few weeks, especially in C57BL/6 mice. Mac-1
D A C Botte et al.
Clinical and experimental immunology, 177(2), 381-390 (2014-03-29)
Alpha-melanocyte stimulating hormone (α-MSH) is a neuropeptide exhibiting anti-inflammatory activity in experimental models of autoimmune diseases. However, no studies thus far have examined the effects of α-MSH on systemic lupus erythematosus (SLE). This study aimed to determine the effects of
Sae Won Kim et al.
Oncotarget, 5(5), 1226-1240 (2014-04-10)
Identification of novel biomarkers for tumor-initiating cells (TICs) is of critical importance for developing diagnostic and therapeutic strategies against cancers. Here we identified the role of KIAA1114, a full-length translational product of the trophinin gene, as a distinctive marker for
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