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SAFC

MOPS

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Synonym(s):
3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid
Empirical Formula (Hill Notation):
C7H15NO4S
CAS Number:
1132-61-2
Molecular Weight:
209.26
Beilstein:
1106776
EC Number:
214-478-5
MDL number:
MFCD00006183
NACRES:
NA.21

biological source

synthetic

Quality Level

400

Assay

≥99.5%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, microbial, and trace metals; tested

pH

2.5-4 (1 M in H2O)

useful pH range

6.5-7.9

pKa (25 °C)

7.2

λ

1 M in H2O

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES string

OS(=O)(=O)CCCN1CCOCC1

InChI

1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)

InChI key

DVLFYONBTKHTER-UHFFFAOYSA-N

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General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Application

MOPS is a biological buffer also referred to as a “Propane Sultone” buffer. The pKa of MOPS is 7.01 which make it an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MOPS is considered to be non-toxic to culture cell lines and provides high-solution clarity.

MOPS is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream). MOPS based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

replaced by

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup

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