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Merck
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PLA0111

Rabbit anti-Lasu1/Ureb1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

ARF-BP1, ARF-binding protein 1, BJ-HCC-24 tumor antigen, HECT, HECT domain protein LASU1, HECTH9, HSPC272, Ib772, KIAA0312, LASU1, MULE, Mcl-1 ubiquitin ligase E3, UBA and WWE domain containing 1, UBA and WWE domain-containing protein 1, URE-B1, URE-binding protein 1, UREB1, homologous to E6AP carboxyl terminus homologous protein 9, large structure of UREB1, upstream regulatory element-binding protein 1

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, IP, WB
Citations:
-

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

technique(s)

immunohistochemistry: 1:1000-1:5,000, immunoprecipitation (IP): 2-10 μg/mg, western blot: 1:2,000-1:10,000

accession no.

NP_113584.3

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

rabbit ... Lasu1/Ureb1(10075)

Immunogen

The epitope recognized by PLA0111 maps to a region between residues 1025 and 1075 of human Upstream Regulatory Element Binding Protein 1 using the numbering given in entry NP_113584.2 (GeneID 10075).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Lasu1/Ureb1 is an E3 ubiquitin protein ligase that mediates the ubiquitination of core histones, Mcl-1, Cdc6, and p53. Lasu1/Ureb1 expression is regulated during spermatogenesis and appears to play a role in chromatin modification in germ cells as well as other tissues.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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2

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