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Rabbit anti-Cul4a Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.


biological source


Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies


Powered by Bethyl Laboratories, Inc.

species reactivity

mouse, human


immunohistochemistry: 1:500- 1:2,000
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:1,000- 1:10,000

accession no.


UniProt accession no.

shipped in

wet ice

storage temp.


Gene Information

rabbit ... Cul4a(8451)


The epitope recognized by PLA0136 maps to a region between residue 700 and the C-terminus (residue 759) of human Cullin 4A using the numbering given in entry NP_001008895.1 (GeneID 8451).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

Cul4a is a member of the cullin group of proteins and functions as a scaffold to bring together ubiquitin E3 ligases, E2 conjugating enzyme, and substrate proteins to mediate the ubiquitination of substrate proteins. Several Cul4 E3 ligase complexes have been identified as important in cell cycle regulation and the DNA damage checkpoint response.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Laura P Saucedo-Cuevas et al.
Oncotarget, 5(8), 2330-2343 (2014-05-30)
The CUL4A E3 ubiquitin ligase is involved in the regulation of many cellular processes and its amplification and/or overexpression has been observed in breast cancer. The 13q34 amplification, which is associated with the basal-like breast cancer subtype, has been proposed

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