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Merck
CN

PLA0163

Anti-ATRX Antibody

rabbit polyclonal

Synonym(s):

ATP-dependent helicase ATRX, ATR2, DNA dependent ATPase and helicase, JMS, Juberg-Marsidi syndrome, MRX52, MRXHF1, RAD54, RAD54 homolog (S. cerevisiae), RAD54L, SFM1, SHS, X-linked, X-linked 52, X-linked helicase II, X-linked nuclear protein, XH2, XNP, ZNF-HX, Zinc finger helicase, alpha thalassemia/mental retardation syndrome X-linked (RAD54 (S. cerevisiae) homolog), alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog. S. cerevisiae), helicase 2, mental retardation

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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Product Name

Rabbit anti-ATRX Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human

technique(s)

immunohistochemistry: 1:500-1:2,000
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:1,000-1:5,000

accession no.

NP_000480.2

UniProt accession no.

P46100

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... ATRX(546)

Immunogen

The epitope recognized by PLA0163 maps to a region between residue 2442 and the C-terminus (residue 2492) of human alpha thalassemia/mental retardation syndrome X-linked using the numbering given in entry NP_000480.2 (GeneID 546).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

ATRX (alpha-thalassemia mental retardation X-linked) is a chromatin remodeling protein and transacting regulator of globin gene expression that has been linked to several X-linked mental retardation syndromes and hematologic diseases such as myelodysplasia. ATRX possesses an ATPase/helicase domain and is related to the SWI/SNF family of proteins. Mutations in ATRX have been demonstrated to cause changes in DNA methylation patterns and gene expression important to development.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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