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PLA0172

Rabbit anti-PML Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

MYL, PML/RARA fusion, PP8675, RING finger protein 71, RNF71, TRIM19, inducer of, probable transcription factor PML, promyelocytic leukemia, promyelocytic leukemia protein, tripartite motif protein TRIM19, tripartite motif-containing protein 19

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
immunoprecipitation (IP)
western blot
Species reactivity:
human
Citations:
1
Technique(s):
immunohistochemistry: 1:200- 1:1,000
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000
Uniprot accession no.:
P29590

Key Documents

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Product Name

Rabbit anti-PML Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.

biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

technique(s)

immunohistochemistry: 1:200- 1:1,000
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_150241.2

UniProt accession no.

P29590

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

rabbit ... PML(5371)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

The epitope recognized by PLA0172 maps to a region between residue 375 and 425 of promyelocytic leukemia using the numbering given in entry NP_150241.2 (GeneID 5371).

Other Notes

PML is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. PML is a multifunctional protein involved in activities such as tumor growth suppression, hematopoietic differentiation, gene transcription, apoptotic induction, and viral immunity. PML is often involved in chromosomal translocations with the retinoic acid receptor alpha gene. PML-retinoic acid receptor translocations are associated with acute promyelocytic leukemia.

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Lot/Batch Number
2

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Interplay between PML NBs and HIRA for H3.3 dynamics following type I interferon stimulus.
Kleijwegt, et al.
eLife, 12 (2023)

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