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PLA0218

Sigma-Aldrich

Rabbit anti-IKK-beta Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):
NFKBIKB, I-kappa-B-kinase beta, IkBKB, IKK-beta, nuclear factor NF-kappa-B inhibitor kinase beta, IKK2, IKKB, I-kappa-B kinase 2, IMD15, IKK-B
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human

technique(s)

immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_001547.1

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... IKK-beta(3551)

Immunogen

The epitope recognized by PLA0218 maps to a region between residue 706 and 756 of human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta using the numbering given in entry NP_001547.1 (GeneID 3551).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

IKK-beta (Inhibitor of nuclear factor kappa B kinase subunit beta) is one of three subunits that comprise the IKK complex. The IKK complex consists of two catalytic subunits, IKK-alpha and IKK-beta, and a regulatory subunit IKK-gamma/NEMO. As a kinase, IKK functions to phosphorylate members of the NF-kappa B inhibitor proteins, the I-kappa B proteins. Phosphorylation of I-kappa B proteins results in the ubiquitination and degradation of I kappa B and the release and translocation of the NF-kappa B transcription factor to the nucleus where it may function to activate a vast number of genes.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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