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PLA0228

Sigma-Aldrich

Rabbit anti-Ki-67 IHC Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):
bromodomain-containing 4, Protein HUNK1, HUNKI, CAP, chromosome-associated protein, HUNK1, MCAP
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

mouse, human

concentration

1 mg/mL

technique(s)

immunohistochemistry: 1:1,000-1:5,000
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000-1:10,000

accession no.

NP_002408.2

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... MKI67(4288)

Immunogen

Antibody was affinity purified using an epitope specific to Ki-67 immobilized on solid support. The epitope recognized by PLA0228 maps to a region between residues 1800 and 1850 of human Ki-67 using the numbering given in entry NP_002408.2 (GeneID 4288).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

Ki-67 is a marker of cell proliferation detected in cells that are in G1-, S-, G2-, and M-phase of the cell cycle and absent in cells in G0. Ki-67 is detected exclusively in the nucleus, and its detection by immunohistological methods has proven to have diagnostic and prognostic value in the study of a variety of human tumors. The specific cellular functions of Ki-67 have not been elucidated, but it is proposed to function in the organization and maintenance of the architecture of DNA and in the synthesis of ribosomes during mitosis.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Dongzhe Liu et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 39(6), 1010428317701443-1010428317701443 (2017-06-21)
Increasing evidence suggests that the glutathione peroxidase 2 may actually play important roles in tumorigenesis and progression in various human cancers such as colorectal carcinomas and lung adenocarcinomas. However, the role of glutathione peroxidase 2 in gastric carcinoma remains to
Heber Amilcar Martins et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 39(3), 1010428317695960-1010428317695960 (2017-03-28)
We evaluated the effects of supplementation with oral l-glutamine in Walker-256 tumor-bearing rats. A total of 32 male Wistar rats aged 54 days were randomly divided into four groups: rats without Walker-256 tumor, that is, control rats (C group); control

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