PLA0233
Rabbit anti-BCR Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
Synonym(s):
ALL, BCR/FGFR1 chimera protein, BCR1, CML, D22S11, D22S662, FGFR1/BCR chimera protein, PHL, breakpoint cluster region, renal carcinoma antigen NY-REN-26
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Species reactivity:
human
Technique(s):
flow cytometry: 0.25 μg, immunofluorescence: 1:500- 1:2,000, immunoprecipitation (IP): 10 μg/mg
Application:
FACS, IF, IP
Citations:
-
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
species reactivity
human
technique(s)
flow cytometry: 0.25 μg, immunofluorescence: 1:500- 1:2,000, immunoprecipitation (IP): 10 μg/mg
accession no.
NP_004318.3
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
rabbit ... BCR(613)
Immunogen
The epitope recognized by PLA0233 maps to a region between residue 50 and 100 of human breakpoint cluster region using the numbering given in entry NP_004318.3 (GeneID 613).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
BCR (breakpoint cluster region) was identified as part of a fusion protein that results from a reciprocal translocation with the ABL gene between chromosomes 22 and 9. The BCR-ABL fusion is the cause of chronic myeloid leukemia (CML). The BCR protein contains a C2 domain, a DBL-homology domain, a PH domain, and a Rho-GAP domain and functions as a GTPase-activating protein for RAC1 and CDC42.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| PLA0233-100UL | 04061837723407 |