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Merck
CN

PLA0256

Rabbit anti-WDR5 Antibody, Affinity Purified

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Synonym(s):

BIG-3, BMP2-induced 3-kb gene protein, CFAP89, SWD3, Set1c WD40 repeat protein, cilia and flagella associated protein 89, homolog, homolog (S. cerevisiae)

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, PLA, WB
Citations:
1

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse, rat

technique(s)

immunohistochemistry: 1:200- 1:1,000, proximity ligation assay: suitable, western blot: 1:2,000-1:10,000

accession no.

NP_060058.1

UniProt accession no.

P61964

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

rabbit ... WDR5(11091)

Immunogen

The epitope recognized by PLA0256 maps to a region between residue 50 and 100 of human WD repeat domain 5 using the numbering given in entry NP_060058.1 (GeneID 11091).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

WD-repeat domain 5 (WDR5) is a member of the WD repeat family. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WDR5 contains 7 WD repeats and is a core subunit of the human MLL and SET1 histone H3 lys4 methyltransferase complexes. WDR5 functions in facilitating the assembly of MLL and SET1 chromatin-modifiying complexes.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Xiaoping Wang et al.
Frontiers in immunology, 9, 2615-2615 (2018-12-18)
Streptococcus suis (S. suis) ranks among the five most important porcine pathogens worldwide and occasionally threatens human health, particularly in people who come into close contact with pigs or pork products. An S. suis infection induces the formation of neutrophil

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