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Merck
CN

PLA0265

Sigma-Aldrich

Rabbit anti-TNIK Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

KIAA0551

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

technique(s)

immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_055843.1

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... TNIK(23043)

Immunogen

The epitope recognized by PLA0265 maps to a region between residue 600 and 650 of human TRAF2 and NCK interacting kinase using the numbering given in entry NP_055843.1 (GeneID 23043).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

TNIK (TRAF2 and NCK-interacting protein kinase) is a serine threonine kinase that acts as an essential activator of the Wnt signaling pathway. TNIK is recruited to promoters of Wnt target genes and is required to activate Wnt target genes expression. TNIK may also play a role in the response to environmental stress and appears to act upstream of the JUN N-terminal pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UKE5].

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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