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PLA0300

Sigma-Aldrich

Goat anti-CRSP1/TRAP220 Antibody, Affinity Purified

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Synonym(s):
ARC205, CRSP1, CRSP200, DRIP205, DRIP230, Mediator complex subunit 1, PBP, PPAR binding protein, PPAR-binding protein, PPARBP, PPARG binding protein, PPARGBP, RB18A, TR-interacting protein 2, TRAP220, TRIP-2, TRIP2, activator-recruited cofactor 205 kDa component, p53 regulatory protein RB18A, peroxisome proliferator-activated receptor-binding protein, thyroid hormone receptor-associated protein complex 220 kDa component, thyroid hormone receptor-associated protein complex component TRAP220, thyroid receptor interacting protein 2, thyroid receptor-interacting protein 2, vitamin D receptor-interacting protein 230 kD, vitamin D receptor-interacting protein complex component DRIP205

biological source

goat

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

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species reactivity

human, mouse

concentration

1 mg/mL

technique(s)

immunohistochemistry: 1:500-1:2,000
immunoprecipitation (IP): 2- 10 μg/mg
western blot: 1:500- 1:2,500

accession no.

NP_004765.2

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

goat ... CRSP1/TRAP220(5469)

Immunogen

The epitope recognized by PLA0300 maps to a region between residue 1531 and 1581 of human Cofactor Required for Sp1 Transcriptional Activation 1/Thyroid Hormone Receptor-Associated Protein Complex Component using the numbering given in entry NP_004765.2 (GeneID 5469).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

CSP1/TRAP220 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15648].

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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