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PLA0307

Goat anti-Sp1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

specificity protein 1

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
immunoprecipitation (IP)
western blot
Species reactivity:
mouse, human
Citations:
1
Technique(s):
immunohistochemistry: 1:1,000-1:5,000
immunoprecipitation (IP): 2- 10 μg/mg
western blot: 1:2,000- 1:10,000
Uniprot accession no.:
P08047

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Product Name

Goat anti-Sp1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.

biological source

goat

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human

concentration

1 mg/mL

technique(s)

immunohistochemistry: 1:1,000-1:5,000
immunoprecipitation (IP): 2- 10 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_612482.2

UniProt accession no.

P08047

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

goat ... Sp1(6667)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

The epitope recognized by PLA0307 maps to a region between residue 735 to 785 of human Sp1 Transcription Factor using the numbering given in entry NP_612482.2 (GeneID 6667).

Other Notes

Specificity protein 1 (Sp1) is the original member of the Sp1-like/KLF family of zinc-finger transcription factors that binds GC-rich DNA elements to regulate transcription of genes involved in a variety of cellular functions. Sp-1 interacts with coactivators such as p300/CBP, TAFII130, and CRSP.

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
1

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Maxime Cahuzac et al.
Communications biology, 5(1), 251-251 (2022-03-24)
Poly (ADP-ribose) polymerase 1 (PARP1) plays an essential role in DNA repair and is targeted by anticancer therapies using PARP inhibitors (PARPi) such as olaparib. PARPi treatment in prostate cancer (PC) is currently used as a monotherapy or in combination

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