PLA0307
Goat anti-Sp1 Antibody, Affinity Purified
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Synonym(s):
specificity protein 1
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, IP, WB
Citations:
1
biological source
goat
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human
concentration
1 mg/mL
technique(s)
immunohistochemistry: 1:1,000-1:5,000, immunoprecipitation (IP): 2- 10 μg/mg, western blot: 1:2,000- 1:10,000
accession no.
NP_612482.2
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
goat ... Sp1(6667)
Immunogen
The epitope recognized by PLA0307 maps to a region between residue 735 to 785 of human Sp1 Transcription Factor using the numbering given in entry NP_612482.2 (GeneID 6667).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
Specificity protein 1 (Sp1) is the original member of the Sp1-like/KLF family of zinc-finger transcription factors that binds GC-rich DNA elements to regulate transcription of genes involved in a variety of cellular functions. Sp-1 interacts with coactivators such as p300/CBP, TAFII130, and CRSP.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Maxime Cahuzac et al.
Communications biology, 5(1), 251-251 (2022-03-24)
Poly (ADP-ribose) polymerase 1 (PARP1) plays an essential role in DNA repair and is targeted by anticancer therapies using PARP inhibitors (PARPi) such as olaparib. PARPi treatment in prostate cancer (PC) is currently used as a monotherapy or in combination
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