APH1 (anterior pharynx defective-1) is a component of γ-secretase complex. It is located on chromosome 1q21. It has 2 unique isoforms such as APH1a, located on chromosome 1 and APH1b, located on chromosome 15 (3).
a 18 amino acid peptide from near the center of human APH1.
APH1 (anterior pharynx defective-1) participates in the secretase like activity. Throughout the embryonic development, APH1 participates in presenilin dependent function.
The action of this antibody can be blocked using blocking peptide SBP4003.
Solution in phosphate buffered saline containing 0.02% sodium azide
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