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PZ0015

Trovafloxacin mesylate

>98% (HPLC), powder, Pannexin 1 inhibitor

Synonym(s):

(1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate, CP-99219-27, Trovafloxacin methanesulfonate

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About This Item

Empirical Formula (Hill Notation):
C20H15F3N4O3 · CH3SO3H
CAS Number:
147059-75-4
Molecular Weight:
512.46
UNSPSC Code:
12352200
PubChem Substance ID:
329823684
NACRES:
NA.77
MDL number:
MFCD00913361
Assay:
>98% (HPLC)
Form:
powder
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Product Name

Trovafloxacin mesylate, >98% (HPLC)

assay

>98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: >10 mg/mL

storage temp.

room temp

SMILES string

CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F

InChI

1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;

InChI key

DYNZICQDCVYXFW-AHZSKCOESA-N

Application

Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures. It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.

Biochem/physiol Actions

Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.
Trovafloxacin mesylate is a broad spectrum antibiotic.
Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

hcodes

H314,H361

Hazard Classifications

Repr. 2 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

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