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Merck
CN

PZ0022

BLI-489 hydrate

≥98% (HPLC), β-lactamase inhibitor, powder

Synonym(s):

6-[(5,6-Dihydro-8H-imidazo[2,1-c][1,4]oxazin-2-yl)methylene]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid sodium salt hydrate, WAY-185489

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About This Item

Empirical Formula (Hill Notation):
C13H10N3NaO4S · xH2O
CAS Number:
Molecular Weight:
327.29 (anhydrous basis)
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
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Product Name

BLI-489 hydrate, ≥98% (HPLC)

SMILES string

O=C(N1[C@]/2([H])SC=C1C([O-])=O)C2=C\C3=CN4C(COCC4)=N3.[Na+].O

InChI key

UAZCFKAYAYJPDM-UVEQJXRBSA-M

InChI

1S/C13H11N3O4S.Na.H2O/c17-11-8(12-16(11)9(6-21-12)13(18)19)3-7-4-14-10-5-20-2-1-15(7)10;;/h3-4,6,12H,1-2,5H2,(H,18,19);;1H2/q;+1;/p-1/b8-3-;;/t12-;;/m1../s1

assay

≥98% (HPLC)

form

powder

color

yellow

solubility

H2O: >20 mg/mL

storage temp.

room temp

Quality Level

Related Categories

Biochem/physiol Actions

BLI-489 is a penem β-lactamase inhibitor.
BLI-489 is a penem β-lactamase inhibitor, which has shown activity against class A, C, and D β-lactamases. BLI-489 is being tested in combination therapy for drug-resistant bacteria.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1


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Articles

Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.

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