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PZ0035

Sutezolid

Name: Sutezolid
Brand: SIGMA

≥98% (HPLC)

Synonym(s):

(S)-N-[[3-[3-Fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide, PNU-100480, PNU100480

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₂₀FN₃O₃S

CAS Number:

168828-58-8

Molecular Weight:

353.41

NACRES:

NA.77

PubChem Substance ID:

329823692

UNSPSC Code:

51111800

MDL number:

MFCD00937821

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

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Properties

Quality Level

100

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -8 to -12°, c = 1 in chloroform-d

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

room temp

SMILES string

FC1=CC(N(C[C@H](CNC(C)=O)O2)C2=O)=CC=C1N3CCSCC3

InChI

1S/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1

InChI key

FNDDDNOJWPQCBZ-ZDUSSCGKSA-N

Description

Biochem/physiol Actions

Sutezolid (PNU 100480) is an oxazolidinone antimicrobial. Sutezolid inhibits protein synthesis by inhibiting bacterial mRNA translation. Sutezolid is being investigated for the treatment of multiple drug–resistant and extensively drug-resistant tuberculosis. The compound is a less toxic and more potent derivative of linezolid.

Sutezolid (PNU 100480) is an oxazolidinone antimicrobial; antitubercular; inhibits bacterial mRNA translation.