PZ0129
CP-380736
≥98% (HPLC)
Synonym(s):
6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone, PF-00520893
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About This Item
Empirical Formula (Hill Notation):
C14H18N2O5
CAS Number:
Molecular Weight:
294.30
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
off-white to light tan
solubility
DMSO: ≥10 mg/mL
storage temp.
room temp
SMILES string
COCCOc1cc2N=CNC(=O)c2cc1OCCOC
InChI
1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
InChI key
PMQWTUWLIGJTQD-UHFFFAOYSA-N
Biochem/physiol Actions
CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.
CP-380736 is selective inhibitor of epidermal growth factor receptor.
Features and Benefits
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Storage Class
11 - Combustible Solids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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