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Merck
CN

PZ0284

PF-04753299

≥98%

Synonym(s):

α(R)-N-Hydroxy-α-methyl-α-(methylsulfonyl)-[1,1′-biphenyl]-4-butanamide, (+)-(2R)-4-(Biphenyl-4-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2R)-4-Biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, PF 04753299, PF-4753299

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About This Item

Empirical Formula (Hill Notation):
C18H21NO4S
CAS Number:
1289620-49-0
Molecular Weight:
347.43
NACRES:
NA.77
PubChem Substance ID:
329823811
UNSPSC Code:
51111800
MDL number:
MFCD22683864

Key Documents

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InChI

1S/C18H21NO4S/c1-18(17(20)19-21,24(2,22)23)13-12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11,21H,12-13H2,1-2H3,(H,19,20)/t18-/m1/s1

SMILES string

O=C(NO)[C@@](S(=O)(C)=O)(C)CCC(C=C1)=CC=C1C2=CC=CC=C2

InChI key

GDYIQUFNICPYHF-GOSISDBHSA-N

assay

≥98%

form

powder

color

white to light brown

solubility

DMSO: 20 mg/mL, clear

storage temp.

room temp

Quality Level

100

Biochem/physiol Actions

PF-04753299 is a potent and selective inhibitor of LpxC (UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase) that is effective in a murine of gram-negative bacteria infection model.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000132281
0000115844
0000115842
0000058528
085M4757V

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