PZ0284

PF-04753299

Name: PF-04753299
Brand: SIGMA

≥98%

别名:

α(R)-N-Hydroxy-α-methyl-α-(methylsulfonyl)-[1,1′-biphenyl]-4-butanamide, (+)-(2R)-4-(Biphenyl-4-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2R)-4-Biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, PF 04753299, PF-4753299

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关于此项目

经验公式（希尔记法）:

C₁₈H₂₁NO₄S

化学文摘社编号:

1289620-49-0

分子量:

347.43

NACRES:

NA.77

PubChem Substance ID:

329823811

UNSPSC Code:

51111800

MDL number:

MFCD22683864

主要文件

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InChI

1S/C18H21NO4S/c1-18(17(20)19-21,24(2,22)23)13-12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11,21H,12-13H2,1-2H3,(H,19,20)/t18-/m1/s1

SMILES string

O=C(NO)[C@@](S(=O)(C)=O)(C)CCC(C=C1)=CC=C1C2=CC=CC=C2

InChI key

GDYIQUFNICPYHF-GOSISDBHSA-N

assay

≥98%

form

powder

color

white to light brown

solubility

DMSO: 20 mg/mL, clear

storage temp.

room temp

Quality Level

100

Biochem/physiol Actions

PF-04753299 is a potent and selective inhibitor of LpxC (UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase) that is effective in a murine of gram-negative bacteria infection model.