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PZ0301

PF-06284674

≥98% (HPLC)

Synonym(s):

2-(1H-Benzimidazol-1-ylmethyl)-6-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

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About This Item

Empirical Formula (Hill Notation):
C17H14N4O
CAS Number:
1434288-24-0
Molecular Weight:
290.32
NACRES:
NA.77
PubChem Substance ID:
329823823
UNSPSC Code:
51111800
MDL number:
MFCD29037211
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to brown

solubility

DMSO: 10 mg/mL, clear

storage temp.

room temp

SMILES string

O=C1N2C(C=CC=C2C)=NC(CN(C=N3)C4=C3C=CC=C4)=C1

InChI

1S/C17H14N4O/c1-12-5-4-8-16-19-13(9-17(22)21(12)16)10-20-11-18-14-6-2-3-7-15(14)20/h2-9,11H,10H2,1H3

InChI key

ICTBPKWPCGSFPZ-UHFFFAOYSA-N

Biochem/physiol Actions

PF-06284674 is a cell permeable, potent and selective M2 isoform of pyruvate kinase (PKM2) activator.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Codes

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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