PZ0343
PF-06260414
≥98% (HPLC)
Synonym(s):
6-[(4R)-tetrahydro-4-methyl-1,1-dioxido-2H-1,2,6-thiadiazin-2-yl]-1-isoquinolinecarbonitrile
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About This Item
Empirical Formula (Hill Notation):
C14H14N4O2S
CAS Number:
Molecular Weight:
302.35
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Quality Level
assay
≥98% (HPLC)
form
powder
color
light orange to dark orange
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
room temp
SMILES string
C[C@H](CNS1(=O)=O)CN1C2=CC3=CC=NC(C#N)=C3C=C2
InChI
1S/C14H14N4O2S/c1-10-8-17-21(19,20)18(9-10)12-2-3-13-11(6-12)4-5-16-14(13)7-15/h2-6,10,17H,8-9H2,1H3/t10-/m1/s1
InChI key
ZKAVFOXYJCREBQ-SNVBAGLBSA-N
Biochem/physiol Actions
PF-06260414 is a nonsteriodal selective androgen receptor modulator (SARM). PF-06260414 is being investigated as a treatment for muscle weakening such as that associated with muscular dystrophy and the sarcopenia associated with natural aging. PF-06260414 has anabolic activity without unwanted androgenic activity on reproductive organs, liver or kidneys.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Emiliano Ventura et al.
Journal of chromatography. A, 1600, 183-196 (2019-05-06)
A semi-quantitative method was developed to monitor the misuse of 15 SARM compounds belonging to nine different families, in urine matrices from a range of species (equine, canine, human, bovine and murine). SARM residues were extracted from urine (200 μL) with
Global Trade Item Number
| SKU | GTIN |
|---|---|
| PZ0343-25MG | 04061832273600 |
| PZ0343-5MG | 04061832273617 |