PZ0401
PF-06855800 variable hydrate
≥98% (HPLC)
Synonym(s):
(2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-(4-chloro-3-fluorophenyl)(hydroxy)methyl)tetrahydrofuran-3,4-diol, 7-[(5R)-5-C-(4-Chloro-3-fluorophenyl)-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
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About This Item
Empirical Formula (Hill Notation):
C17H16ClFN4O4 · xH2O
Molecular Weight:
394.78 (anhydrous basis)
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
PF-06855800 is a cell penetrant, potent and selective S-adenosylmethionine (SAM) competitive inhibitor of the protein arginine methyltransferase 5 (PRMT5) that exhibits anticancer activity in both in vitro and in vivo models.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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