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About This Item
Empirical Formula (Hill Notation):
C14H15F3N8OS
CAS Number:
Molecular Weight:
400.38
UNSPSC Code:
12352200
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
FC(F)(C1=NC2=C(C(N)=N1)N=NN2C[C@@H]3OCCN(C3)CC4=NC=CS4)F
InChI
1S/C14H15F3N8OS/c15-14(16,17)13-20-11(18)10-12(21-13)25(23-22-10)6-8-5-24(2-3-26-8)7-9-19-1-4-27-9/h1,4,8H,2-3,5-7H2,(H2,18,20,21)/t8-/m1/s1
InChI key
VNLPYEMGHGDRRZ-MRVPVSSYSA-N
Biochem/physiol Actions
PF-04957325 is a cAMP-competitive, potent and selective phosphodiesterase 8 inhibitor (IC50 = 3.05 nM/PDE8A, 0.44 nM/PDE8B, 1 μM/PDE4D with 12-14 nM cAMP; >1 μM/all other PDEs).
signalword
Danger
hcodes
Hazard Classifications
Self-react. C
Storage Class
5.2 - Organic peroxides and self-reacting hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| PZ0407-25MG | 04065265932738 |
| PZ0407-5MG | 04065265932745 |
