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R0655

Anti-Ribosomal Protein L26 (N-terminal) antibody produced in rabbit

Name: Anti-Ribosomal Protein L26 (N-terminal) antibody produced in rabbit
Brand: SIGMA

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-RPL26

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD09265375

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IF, IP, WB

Citations:

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Properties

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 17 kDa

species reactivity

mouse, human, rat

concentration

~1 mg/mL

technique(s)

immunoprecipitation (IP): 5-10 μg using HEK-293T cell lysates, indirect immunofluorescence: 5-10 μg/mL using paraformaldehye-fixed HeLa cells, western blot: 0.5-1 μg/mL using HEK-293T cell extracts

UniProt accession no.

P61254

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RPL26(6154)
mouse ... Rpl26(19941)
rat ... Rpl26(287417)

Description

General description

RPL26 (ribosomal protein L26) is located on chromosome 17. It codes for a 145-amino-acid long protein and has four exons. It is present on the large ribosomal subunit.

Ribosomal protein L26 is one of the large ribosomal subunit proteins.

Immunogen

synthetic peptide corresponding to amino acids 1-17 of human ribosomal protein L26, conjugated to KLH via a C-terminal added cysteine residue. The sequence is conserved in human, rat, and mouse.

Application

Anti-Ribosomal Protein L26 (N-terminal) antibody produced in rabbit has been used in:

immunoblotting
immunoprecipitation
immunostaining
immunofluorescence
coimmunoprecipitation analysis

Biochem/physiol Actions

Anti-Ribosomal Protein L26 (N-terminal) specificallyrecognizes human Ribosomal Protein L26.

RPL26 (ribosomal protein L26) regulates the expression of p73. It plays an important role in translation and stability of ribosomes. RPL26 frameshift mutation can cause several physical abnormalities.

Ribosomal proteins are implicated in mRNA recognition, tRNA recognition and decoding and nuclear export. It was shown together with nucleolin to bind to the 5′ untranslated region of p53 mRNA and to control p53 translation and induction after DNA damage.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

低风险生物材料

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number

0000473286

0000458936

0000237213

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Global Trade Item Number

SKU	GTIN
R0655-200UL	04061838032584