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R1283

Rhodblock 6

≥98% (HPLC)

Synonym(s):

N-1H-Indazol-5-yl-cyclobutanecarboxamide

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About This Item

Empirical Formula (Hill Notation):
C12H13N3O
CAS Number:
886625-06-5
Molecular Weight:
215.25
NACRES:
NA.77
PubChem Substance ID:
329823999
UNSPSC Code:
12352200
MDL number:
MFCD07612857
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

faintly bluish, off-white

solubility

DMSO: ≥20 mg/mL

storage temp.

room temp

SMILES string

O=C(Nc1ccc2[nH]ncc2c1)C3CCC3

InChI

1S/C12H13N3O/c16-12(8-2-1-3-8)14-10-4-5-11-9(6-10)7-13-15-11/h4-8H,1-3H2,(H,13,15)(H,14,16)

InChI key

GXJXOQKXBIPBKB-UHFFFAOYSA-N

Biochem/physiol Actions

Rhodblock 6 is an inhibitor of the Rho Kinase pathway.
Rhodblock 6 is an inhibitor of the Rho Kinase pathway. Rhodblock 6 directly inhibited Rok and its human ortholog ROCK I in a kinase assay.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Codes

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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