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R1512

Retinyl palmitate

Name: Retinyl palmitate
Brand: SIGMA

potency: ≥1,700,000 USP units per g

Synonym(s):

Vitamin A palmitate, all−trans−Retinol palmitate

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About This Item

Empirical Formula (Hill Notation):

C₃₆H₆₀O₂

CAS Number:

79-81-2

Molecular Weight:

524.86

UNSPSC Code:

12352205

NACRES:

NA.79

PubChem Substance ID:

24899347

EC Number:

201-228-5

Beilstein/REAXYS Number:

1917366

MDL number:

MFCD00019414

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Properties

biological source

synthetic (organic)

Quality Segment

200

form

solid or viscous liquid

potency

≥1,700,000 USP units per g

does not contain

antioxidant

color

yellow to yellow-green

mp

26 °C

storage temp.

2-8°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1

InChI

1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+

InChI key

VYGQUTWHTHXGQB-FFHKNEKCSA-N

Description

General description

Retinyl palmitate or vitamin A palmitate is a retinoid, which is an acid form of vitamin A. Retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinyl palmitate is a major storage form of vitamin A found in epidermis. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed.

Application

Retinyl palmitate has been used as a standard in high performance liquid chromatography (HPLC). It has also been used to study its effect on brain regeneration in larval Xenopus laevis.

Biochem/physiol Actions

Retinyl palmitate is widely used in pharmaceutical applications. It is also extensively used in cosmetic formulations due to its beneficial effects on the appearance of skin and anti-oxidant properties. Retinyl palmitate acts as a teratogen and affect vertebrate embryogenesis and regeneration. It is added as a source of vitamin A in low fat and skim milks. Retinyl palmitate acts as a chemopreventive or antineoplastic agent.

Review: Vitamin A metabolism.

Packaging

Sealed ampule.

Physical form

oil or solid

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Pictograms

GHS08

Signal Word

Danger

Hazard Codes

H360D,H412

Precautionary Statements

P202 - P273 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Aquatic Chronic 3 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point (°F)

No data available

Flash Point (°C)