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R1512

Retinyl palmitate

Name: Retinyl palmitate
Brand: SIGMA

potency: ≥1,700,000 USP units per g

Synonym(s):

Vitamin A palmitate, all−trans−Retinol palmitate

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About This Item

Empirical Formula (Hill Notation):

C₃₆H₆₀O₂

CAS Number:

79-81-2

Molecular Weight:

524.86

UNSPSC Code:

12352205

NACRES:

NA.79

PubChem Substance ID:

24899347

EC Number:

201-228-5

Beilstein/REAXYS Number:

1917366

MDL number:

MFCD00019414

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biological source

synthetic (organic)

Quality Level

200

form

solid or viscous liquid

potency

≥1,700,000 USP units per g

does not contain

antioxidant

color

yellow to yellow-green

mp

26 °C

storage temp.

2-8°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1

InChI

1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+

InChI key

VYGQUTWHTHXGQB-FFHKNEKCSA-N

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Related Categories

Biochemicals

Cell Culture Supplements & Reagents

Vitamins

General description

Retinyl palmitate or vitamin A palmitate is a retinoid, which is an acid form of vitamin A. Retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinyl palmitate is a major storage form of vitamin A found in epidermis. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed.

Application

Retinyl palmitate has been used as a standard in high performance liquid chromatography (HPLC). It has also been used to study its effect on brain regeneration in larval Xenopus laevis.

Biochem/physiol Actions

Retinyl palmitate is widely used in pharmaceutical applications. It is also extensively used in cosmetic formulations due to its beneficial effects on the appearance of skin and anti-oxidant properties. Retinyl palmitate acts as a teratogen and affect vertebrate embryogenesis and regeneration. It is added as a source of vitamin A in low fat and skim milks. Retinyl palmitate acts as a chemopreventive or antineoplastic agent.

Review: Vitamin A metabolism.

Packaging

Sealed ampule.

Physical form

oil or solid

pictograms

GHS08

signalword

Danger

hcodes

H360D,H412

pcodes

P202 - P273 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Aquatic Chronic 3 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Topical application of retinyl palmitate-loaded nanotechnology-based drug delivery systems for the treatment of skin aging

Oliveira MB, et al.

BioMed Research International (2014)

Fundamentals of Dairy Chemistry (2012)

Characterization of bacteriocins produced by two strains of Lactobacillus plantarum isolated from Beloura and Chouriço, traditional pork products from Portugal.

S D Todorov et al.

Meat science, 84(3), 334-343 (2010-04-09)

Bacteriocins bacST202Ch and bacST216Ch, produced by Lactobacillus plantarum strains isolated from Beloura and Chouriço, respectively, inhibited the growth of a number of Gram-positive and Gram-negative meat spoilage bacteria. According to trycine-SDS-PAGE, bacST202Ch and bacST216Ch are approximately 3.5 and 10.0 kDa

The effect of retinyl-palmitate on brain regeneration of larval Xenopus laevis

Bernardini S, et al.

Italian Journal of Zoology, 77(3), 261-271 (2010)

Anticancer activity and mechanism of action of retinoids in oral and pharyngeal cancer

Klaassen I and Braakhuis BJM

Oral Oncology, 38(6) (2002)

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Global Trade Item Number

SKU	GTIN
R1512-25G	04061836694418
R1512-5G	04061836694425

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