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Merck
CN

R2156

Relaxin-1 human

recombinant, expressed in E. coli, >95% (SDS-PAGE), lyophilized powder

Synonym(s):

RLN1, RLXH1, Relaxin 1

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About This Item

CAS Number:
NACRES:
NA.26
UNSPSC Code:
12352202
Form:
lyophilized powder
Assay:
>95% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Mol wt:
(Contains two disulfide-linked subunits: A chain ~2.8 kDa B chain ~3.3 kDa)
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biological source

human

recombinant

expressed in E. coli

assay

>95% (SDS-PAGE)

form

lyophilized powder

mol wt

(Contains two disulfide-linked subunits: A chain ~2.8 kDa B chain ~3.3 kDa)

technique(s)

cell culture | mammalian: suitable

suitability

endotoxin tested

UniProt accession no.

storage temp.

−20°C

Quality Level

Gene Information

human ... RLN1(6013)

General description

Cell signaling hormone that is prominent in the prostate, and belongs to the insulin superfamily

Biochem/physiol Actions

Relaxin 1 may function in regulating blood pressure, controlling heart rate, and releasing oxytocin and vasopressin
Relaxin has been shown to have antifibrotic effects in renal fibroblasts through mechanisms that increase collagenase activity and via TGF-β signaling.

Physical form

Lyophilized powder containing BSA

Preparation Note

In Phosphate buffered saline solution containing at least 0.1% serum albumin. The concentration should be ≥10 μg/mL

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Rosemary Masterson et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 19(3), 544-552 (2004-02-10)
Renal fibroblasts are important effector cells in tubulointerstitial fibrosis, with experimental antifibrotic strategies focusing on the functional down-regulation of these cells. Several experimental models of fibrosis have provided evidence for the effectiveness of the polypeptide hormone relaxin as a potential

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