R3150
Monoclonal Anti-RhoGAP (p190) antibody produced in mouse
clone D2D6, purified immunoglobulin, buffered aqueous solution
Synonym(s):
Anti-p190, Anti-GRLF1, Anti-Glucorticoid Receptor Binding Factor 1
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About This Item
Conjugate:
unconjugated
Clone:
D2D6, monoclonal
Application:
IP, WB
Citations:
1
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
D2D6, monoclonal
form
buffered aqueous solution
mol wt
antigen ~190 kDa
species reactivity
mouse, rat, monkey, human
technique(s)
immunoprecipitation (IP): 4 μg using 500 μg of a human A431 cell RIPA lysate, western blot: 0.5-2 μg/mL using RIPA lysates from human A431 cells
isotype
IgG
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... GRLF1(2909)
mouse ... Grlf1(232906)
rat ... Grlf1(306400)
Immunogen
GST fusion protein corresponding to amino acids 180-610 of rat p190 RhoGAP.
Physical form
Solution in 0.1 M Tris-glycine, pH 7.4, containing 0.15 sodium chloride and 0.05% sodium azide.
Preparation Note
Purified using protein G.
Other Notes
RhoGAP appears to couple signal transduction via Ras and Rho through its association with RasGAP.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Datasheet
Brajendra K Tripathi et al.
The Journal of cell biology, 218(9), 3060-3076 (2019-07-17)
SRC and ERK kinases control many cell biological processes that promote tumorigenesis by altering the activity of oncogenic and tumor suppressor proteins. We identify here a physiological interaction between DLC1, a focal adhesion protein and tumor suppressor, with SRC and
Global Trade Item Number
| SKU | GTIN |
|---|---|
| R3150-200UG | 04061833631638 |