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R4127

Rhodamine 6G

Dye content ~95 %, Powder

Synonym(s):

Basic Red 1

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About This Item

Linear Formula:
C28H31N2O3Cl
CAS Number:
989-38-8
Molecular Weight:
479.01
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24899367
EC Number:
213-584-9
MDL number:
MFCD00012665
Beilstein/REAXYS Number:
3900071
Colour Index Number:
45160
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Product Name

Rhodamine 6G, Dye content ~95 %

form

powder

Quality Level

200

composition

Dye content, ~95%

technique(s)

titration: suitable

mp

215 °C

solubility

H2O: 1 mg/mL (Red to Very Dark Red)

density

1.3 g/cm3

εmax

≥1700 at 525 nm in water

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Cl.CCNc1cc2OC3=CC(=N/CC)\C(C)=CC3=C(c2cc1C)c4ccccc4C(=O)OCC

InChI

1S/C28H30N2O3.ClH/c1-6-29-23-15-25-21(13-17(23)4)27(19-11-9-10-12-20(19)28(31)32-8-3)22-14-18(5)24(30-7-2)16-26(22)33-25;/h9-16,29H,6-8H2,1-5H3;1H/b30-24+;

InChI key

VYXSBFYARXAAKO-WTKGSRSZSA-N

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Application

Rhodamine 6G has been used as a leukocyte marker to study the interaction between leukocytes and the vascular endothelium. It has also been used to label platelets.

Biochem/physiol Actions

Rhodamine 6G is a rhodamine analog useful in P-glycoprotein (Pgp) efflux assays. It has been used to characterize kinetics of multidrug resistance protein 1 (MRP1)-mediated efflux.
A rhodamine analog useful in Pgp efflux assays. Has been used to characterize kinetics of MRP1- mediated efflux.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP4663
BCCN0586
BCCM0786
BCCL1501
BCCL1500

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Şefik E Erdener et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 41(2), 236-252 (2020-04-03)
Ever since the introduction of thrombolysis and the subsequent expansion of endovascular treatments for acute ischemic stroke, it remains to be identified why the actual outcomes are less favorable despite recanalization. Here, by high spatio-temporal resolution imaging of capillary circulation
Impact of pore size on the vascularization and
osseointegration of ceramic bone substitutes in vivo
Frank M. Klenke
Journal of Biomedical Materials Research (2007)
Kinetic Analysis of Rhodamines Efflux Mediated by the Multidrug Resistance Protein (MRP1)
Chantarawan S
Biophysical Journal, 85(3) (2003)
Induction of P-Glycoprotein by Antiretroviral Drugs in Human Brain Microvessel Endothelial Cells
Gary N.Y. Chan
Antimicrobial Agents and Chemotherapy, 57(9) (2013)
Discoidin Domain Receptor 1 Is a Major Mediator of Inflammation and Fibrosis in Obstructive Nephropathy
Dominique G
The American Journal of Pathology (2011)
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Global Trade Item Number

SKUGTIN
R4127-5G04061836695200
R4127-25G04061822703728
R4127-100G04061835348015

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