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R6527

Reboxetine mesylate hydrate

Name: Reboxetine mesylate hydrate
Brand: SIGMA

>96% (HPLC), noradrenaline uptake inhibitor, solid

Synonym(s):

(2R)-rel-2-[(R)-(2-Ethoxyphenoxy)phenylmethyl]morpholine, Edronax, Vestra

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About This Item

Empirical Formula (Hill Notation):

C₁₉H₂₃NO₃ · CH₃SO₃H · xH₂O

CAS Number:

98769-84-7

Molecular Weight:

409.50 (anhydrous basis)

UNSPSC Code:

12352200

PubChem Substance ID:

24724592

NACRES:

NA.77

MDL number:

MFCD11046031

Assay:

>96% (HPLC)

Form:

solid

Storage condition:

desiccated

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Properties

Product Name

Reboxetine mesylate hydrate, >96% (HPLC), solid

Quality Segment

100

assay

>96% (HPLC)

form

solid

storage condition

desiccated

color

white to tan

solubility

H₂O: >5 mg/mL at ≤60 °C

shipped in

wet ice

storage temp.

2-8°C

SMILES string

O.CS(O)(=O)=O.CCOc1ccccc1O[C@@H]([C@H]2CNCCO2)c3ccccc3

InChI

1S/C19H23NO3.CH4O3S.H2O/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18;1-5(2,3)4;/h3-11,18-20H,2,12-14H2,1H3;1H3,(H,2,3,4);1H2/t18-,19-;;/m1../s1

InChI key

SZPHEVAYLIVGRC-BAMQSBMESA-N

Description

Application

Reboxetine mesylate hydrate has been used as a selective norepinephrine transport blocker:

to study its effects on the surge of dopamine in the cortex of mice brain
to study its anti-immobility effects on the behavior of mice
to analyze its effects on the probabilistic reversal learning task in rodents

Biochem/physiol Actions

Reboxetine mesylate hydrate is a selective noradrenaline uptake inhibitor.

Reboxetine exhibits anti-depressant activity.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c