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Merck
CN

R6775

Anti-Retinoblastoma antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-Rb

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About This Item

UNSPSC Code:
12352203
MDL number:
MFCD00282455

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 105 kDa

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:5,000 using human colon adenocarcinoma tissue, microarray: suitable, western blot: 1:100 using human acute lymphoma Jurkat cell lysate

UniProt accession no.

P06400

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... RB1(5925)

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Immunogen

synthetic peptide corresponding to amino acids 914-928 of the C-terminal region of human p105 retinoblastoma protein (p105 Rb) with N-terminally added cysteine, conjugated to maleimide-activated KLH.

Biochem/physiol Actions

This sequence recognized by the antibody is highly conserved across species (e.g., mouse, rat p105 Rb) and is not found in p107 Rb and p130 Rb.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
117K4802
050K4855

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Luigi Cicatiello et al.
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