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R7882

Retinyl acetate

Name: Retinyl acetate
Brand: SIGMA

solid or viscous liquid, BioReagent, synthetic, suitable for cell culture

Synonym(s):

Retinol acetate, Vitamin A acetate

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About This Item

Empirical Formula (Hill Notation):

C₂₂H₃₂O₂

CAS Number:

127-47-9

Molecular Weight:

328.49

NACRES:

NA.75

PubChem Substance ID:

24899401

eCl@ss:

34058009

UNSPSC Code:

12352205

EC Number:

204-844-2

MDL number:

MFCD00019413

Beilstein/REAXYS Number:

1915439

Assay:

≥90% (HPLC)

Form:

solid or viscous liquid

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biological source

synthetic

Quality Level

200

product line

BioReagent

assay

≥90% (HPLC)

form

solid or viscous liquid

potency

~2,800,000 I.U. per g

mol wt

M_w 328.49 g/mol

technique(s)

cell culture | mammalian: suitable

color

light yellow to dark yellow

mp

57-58 °C

solubility

absolute ethanol: 25 mg/mL (lit.)

storage temp.

−20°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

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Related Categories

Biochemicals

Cell Culture Supplements & Reagents

Vitamins

General description

Retinyl-acetate is a natural and ester derivative of vitamin A. It is found in classical media formulations such as M-199; NCTC-109 and William′s Medium E. Vitamin A is a component of serum useful in most serum containing cell culture systems, which receive some level of vitamin A.

Application

Retinyl acetate has been used as a standard to measure the concentration of vitamin C in high performance liquid chromatography analysis (HPLC) and as a supplement in the preparation of the complete medium.

Biochem/physiol Actions

The oxidized form of retinol is retinoic acid, which has hormone-like growth factor and differentiation activity for epithelial and related cell types, especially neural cells. Retinoic acid induces embryonic stem cells to differentiate towards neural cells. Retinyl-acetate is known to be effective in treating breast cancer.

Preparation Note

The melting point of this material is approx. 58 °C. In order to package, it was melted and may exist as a crystalline solid or as a supercooled viscous liquid.

Other Notes

All trans

pictograms

GHS08

signalword

Danger

hcodes

H360D,H413

pcodes

P202 - P273 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number

0000481217

0000429445

0000429444

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Hormones and Vitamins in Cancer Treatment, 247-247 (1990)

Changes in the composition of yak colostrum during the first week of lactation

Mi JD, et al.

Journal of Dairy Science, 99(1), 818-824 (2016)

The effects of vitamin A supplementation during late-stage pregnancy on longissimus dorsi muscle tissue development, birth traits, and growth performance in postnatal Korean native calves.

Yong Ho Jo et al.

Asian-Australasian journal of animal sciences, 33(5), 742-752 (2020-02-15)

This study investigated the effects of vitamin A (VA) supplementation during late-stage pregnancy on longissimus dorsi muscle tissue development, birth traits, and growth performance of postnatal Korean native calves. In the preliminary experiment, twenty-six pregnant cattle (initial body weight [BW]

Using an adherent cell culture of the mouse subependymal zone to study the behavior of adult neural stem cells on a single-cell level

Ortega F, et al.

Nature Protocols, 6(12), 1847-1847 (2011)

Golden Rice is an effective source of vitamin A.

Guangwen Tang et al.

The American journal of clinical nutrition, 89(6), 1776-1783 (2009-04-17)

Genetically engineered "Golden Rice" contains up to 35 microg beta-carotene per gram of rice. It is important to determine the vitamin A equivalency of Golden Rice beta-carotene to project the potential effect of this biofortified grain in rice-consuming populations that

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Global Trade Item Number

SKU	GTIN
R7882-1G	04061836784935
R7882-5G	04061836801885

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