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Merck
CN

RAB0002

Mouse ACE  ELISA Kit

for serum, plasma and cell culture supernatant

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
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Product Name

Mouse ACE  ELISA Kit, for serum, plasma and cell culture supernatant

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.12 ng/mL
standard curve range: 0.123-30 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Ace(11421)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Mouse ACE ELISA Kit has been used to quantify total serum concentration of angiotensin converting enzyme (ACE) in spontaneously hypertensive rats.

Biochem/physiol Actions

Angiotensin I converting enzyme (ACE) catalyzes the formation of angiotensin II from angiotensin I. ACE is a key aminopeptidase of the renin-angiotensin system. It is a membrane-bound enzyme which is expressed in atherosclerotic lesions.

General description

The Mouse ACE (Angiotensin-Converting Enzyme) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse ACE in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Mouse ACE

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

Corrosion

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Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

Regulatory Information

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A study on the effect of the Dendropanax mobifera extract on anti-hypertensive
Jo YB and Lee JH
Journal of the Korea Academia-Industrial cooperation Society, 17, 708-715 (2016)
Leah K Cuddy et al.
Science translational medicine, 12(563) (2020-10-02)
Recent genome-wide association studies identified the angiotensin-converting enzyme gene (ACE) as an Alzheimer's disease (AD) risk locus. However, the pathogenic mechanism by which ACE causes AD is unknown. Using whole-genome sequencing, we identified rare ACE coding variants in AD families
Local corticosterone production and angiotensin-I converting enzyme shedding in a mouse model of intestinal inflammation
Hanne Salmenkari
World Journal of Gastroenterology (2015)
Nandadeva Lokugamage et al.
Vaccines, 8(1) (2020-02-27)
Chagas cardiomyopathy is caused by Trypanosoma cruzi (Tc). We identified two candidate antigens (TcG2 and TcG4) that elicit antibodies and T cell responses in naturally infected diverse hosts. In this study, we cloned TcG2 and TcG4 in a nanovector and
Angiotensin-Converting Enzyme in Smooth Muscle Cells Promotes Atherosclerosis
Xiaoofeng Chen
Arteriosclerosis, Thrombosis, and Vascular Biology (2016)

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