RAB0018
Apelin EIA Kit
for serum, plasma, culture supernatant and cell lysates
Synonym(s):
Apelin
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About This Item
NACRES:
NA.32
UNSPSC Code:
12352204
species reactivity
rat, mouse, human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, enzyme immunoassay: suitable
input
sample type cell lysate
sample type plasma
sample type serum
sample type culture supernatant(s)
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 5.84 pg/mL
standard curve range: 0.1-1000 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... APLN(8862)
General description
The Apelin C-Terminus Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Apelin C-Terminus peptide based on the principle of Competitive Enzyme Immunoassay. The EIA-APC-1 kit detects all active Apelin peptides, including Apelin-13, Apelin-28, Apelin-31 and Apelin-36.
Immunogen
Apelin, synthetic peptide
Application
For research use only. Not for use in diagnostic procedures.
Apelin EIA kit has been used to determine the concentration of apelin in pre-adipocyte growth medium.
Apelin EIA kit has been used to determine the concentration of apelin in pre-adipocyte growth medium.
Biochem/physiol Actions
Apelin (APLN) is secreted by white adipose tissue. It is an adipokine which has a role in tumor cell progression and vascularization. The protein may have a role in obesity-related disorders. APLN is involved in modulating energy homeostasis, water balance, glucose metabolism and immunity. It has been shown to be upregulated in many cancers.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
Regulatory Information
常规特殊物品
低风险生物材料
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Bogusz Trojanowicz et al.
Toxins, 12(12) (2020-12-02)
Apelin peptides (APLN) serve as second substrates for angiotensin-converting enzyme 2 (ACE2) and, in contrast to angiotensin II (AngII), exert blood-pressure lowering and vasodilatation effects through binding to G-coupled APLN receptor (APLNR). ACE2-mediated cleavage of the APLN may reduce its
Assessment of Apelin Serum Levels in Persistent Atrial Fibrillation and Coronary Artery Disease.
Riazian M
The American Journal of the Medical Sciences (2016)
Apelin Attenuates Oxidative Stress in Human Adipocytes*
Aung Than
The Journal of Biological Chemistry (2014)
Serum apelin levels and body composition changes in breast cancer patients treated with an aromatase inhibitor.
Salman T
Journal of B.U.ON. : Official Journal of the Balkan Union of Oncology (2016)
Apelin as a marker for monitoring the tumor vessel normalization window during antiangiogenic therapy
Li Zhang
Cancer Science (2016)
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Instructions
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