RAB0105
Human Cystatin C ELISA Kit
for serum, plasma, cell culture supernatant and urine
Synonym(s):
Cystatin-3, Cystatin-C
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... CST3(1471)
Input:
sample type plasma
sample type urine
sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type serum
sample type cell culture supernatant(s)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
dry ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type plasma
sample type urine
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 300 pg/mL
standard curve range: 0.313-20 ng/mL
detection method
colorimetric
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... CST3(1471)
General description
The Human Cystatin C ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human cystatin C in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human CystatinC
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Cystatin C (CysC) is released by all nucleated cells. Abnormal thyroid function, immunosuppressive therapy and systemic inflammation alter the levels of CysC. Mutation in the gene encoding CysC causes hereditary cystatin C amyloid angiopathy, which is a consequence of amyloid deposits containing the CysC variant in the brain.
Cystatin-C precursor (CST3) is an inhibitor of lysosomal cysteine proteases and several cathepsins like cathepsin S, a lysosomal enzyme. It has been shown that CST3 is a marker of glomerular filtration and diabetic kidney disease. In the presence of pathological conditions, it forms amyloid fibrils in brain arteries. Mutations in the gene encoding CST3 have been shown to be associated with a form of amyloidosis and age-related macular degeneration.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
10 - Combustible liquids
Regulatory Information
常规特殊物品
低风险生物材料
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Related Content
Instructions
Critical Care Nephrology, 254-254 (2009)
Handbook of Neurochemistry and Molecular Neurobiology: Neural Protein Metabolism and Function, 254-254 (2009)
Yuanyuan Pei et al.
European journal of medical research, 27(1), 39-39 (2022-03-12)
Acute kidney injury (AKI) is a common and critical complication of sepsis, and is associated with unacceptable morbidity and mortality. Current diagnostic criteria for AKI was insensitive for early detection. Novel biomarkers including cystatin C, kidney injury molecule-1 (KIM-1), neutrophil
Global Trade Item Number
| SKU | GTIN |
|---|---|
| RAB0105-1KT | 04061834959878 |