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About This Item
NACRES:
NA.32
UNSPSC Code:
12352200
species reactivity
human, rat, mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, enzyme immunoassay: suitable
input
sample type cell lysate
sample type plasma
sample type serum
sample type culture supernatant(s)
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 1.17 pg/mL
standard curve range: 0.1–1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... GCG(2641)
General description
The GLP-1 Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting GLP-1 peptide based on the principle of Competitive Enzyme Immunoassay.
Immunogen
Glucagon-like Peptide 1 (GLP-1), synthetic peptide
Application
For research use only. Not for use in diagnostic procedures.
Biochem/physiol Actions
Glucagon-Like Peptide I (GLP1) controls the metabolism of glucose by inducing the secretion of insulin and suppressing that of glucagon. Studies in Indonesian population show that reduced levels of this protein are linked with increased susceptibility to type 2 diabetes mellitus. Plasma levels of this hormone also show significant association with systolic and diastolic blood pressure levels.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
10 - Combustible liquids
Regulatory Information
低风险生物材料
常规特殊物品
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Ai-Jun Li et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 310(8), R724-R732 (2016-01-23)
Mercaptoacetate (MA) is an orexigenic agent reported to block fatty acid (FA) oxidation. Recently, however, we reported evidence from isolated nodose ganglion neurons that MA antagonizes the G protein-coupled long- and medium-chain FA receptor GPR40. GPR40 mediates FA-induced secretion of
Maria F Fernandes et al.
International journal of molecular sciences, 23(8) (2022-04-24)
Glucagon-like peptide-1 (GLP-1) potentiates glucose-stimulated insulin secretion (GSIS). While dozens of compounds stimulate GLP-1 secretion, few inhibit. Reduced GLP-1 secretion and impaired GSIS occur in chronic inflammation. Lysophosphatidic acids (LPAs) are bioactive phospholipids elevated in inflammation. The aim of this
Jennifer O Adeghate et al.
Cells, 10(8) (2021-08-28)
The effects of early (5-day) onset of diabetes mellitus (DM) on retina ultrastructure and cellular bioenergetics were examined. The retinas of streptozotocin-induced diabetic rats were compared to those of non-diabetic rats using light and transmission electron microscopy. Tissue localization of
