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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... LCN2(3934)
Input:
sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type urine
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 4.1-1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... LCN2(3934)
General description
Lipocalin-2 (LCN2), a secreted glycoprotein, is an adipokine. It is expressed in various cells like respiratory cells, intestinal epithelial cells, endothelial cells, renal tubular cells and cardiomyocytes. The gene LCN2 is located on human chromosome 9q34. The human lipocalin-2 ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human lipocalin-2 in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human Lipocalin-2
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human Lipocalin-2/NGAL ELISA Kit has been used in the electrochemical immunoassay. It has also been used to determine the neutrophil gelatinase-associated lipocalin (NGAL) levels in the urine.
Biochem/physiol Actions
Lipocalin-2 (LCN2) has been implicated in a variety of processes including cell differentiation, tumorigenesis and apoptosis. Polymorphisms in the expression of LCN2 are associated with many cancers such as breast, colorectal, pancreatic, ovarian, gastric, thyroid, ovarian, bladder and kidney cancers.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
Regulatory Information
含少量动物源组分生物产品
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Quantification of NGAL in Urine of Endurance Cycling Athletes
Machado J C Q, et al.
Journal of physical activity & health, 15(9), 679-682 (2018)
Network based analyses of gene expression profile of LCN2 overexpression in esophageal squamous cell carcinoma
Wu B, et al.
Scientific reports, 5403-5403 (2014)
Lipocalin 2, the TNF-like receptor TWEAKR and its ligand TWEAK act downstream of NFAT1 to regulate breast cancer cell invasion.
Gaudineau B, et. al.
Journal of Cell Science, 125, 4475-4475 (2012)
Kanokporn Pinyopornpanish et al.
Scientific reports, 12(1), 4635-4635 (2022-03-19)
The association between Lipocalin-2 (LCN2) and cognition in patients with metabolic syndrome (MetS) has not been thoroughly investigated. We aimed to evaluate whether serum LCN2 levels are associated with the alteration of cognitive function in patients with MetS. The total
Network based analyses of gene expression profile of LCN2 overexpression in esophageal squamous cell carcinoma
Wu B, et al.
Scientific Reports, 5403-5403 (2014)
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