Skip to Content
Merck
CN

RAB0393

Human Oncostatin M (OSM) ELISA Kit

for serum, plasma, cell culture supernatants and urine

Sign In to View Organizational & Contract Pricing.

Select a Size


About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Human Oncostatin M (OSM) ELISA Kit, for serum, plasma, cell culture supernatants and urine

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 1.37-1000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... OSM(5008)

Application

The Human Oncostatin M (OSM) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Oncostatin M in serum, plasma, cell culture supernatants, and urine.

General description

Oncostatin M (OSM) is a multifunctional hematopoietic cytokine that belongs to the interleukin-6 (IL-6) cytokine family. Human OSM is produced by activated T lymphocytes and monocytes mainly during inflammatory disorders. OSM acts as a cell growth modulator. In addition, it also participates in low-density lipoprotein (LDL) receptor upregulation and induction of hematopoietic factors. OSM contributes to the inflammatory process, autoimmunity, and immunopathogenesis of cancers.

Immunogen

Recombinant Human OSM

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

Regulatory Information

常规特殊物品
低风险生物材料
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Oncostatin M: A mysterious cytokine in cancers.
Masjedi, et al.
International Immunopharmacology, 90, 107158-107158 (2021)
Y Ma et al.
Nucleic acids research, 27(23), 4649-4657 (1999-11-11)
Oncostatin M (OSM), an IL-6 subfamily cytokine, inhibits proliferation and causes morphological changes in many tumor cell lines. GM-CSF, phorbol-12-myristate-13-acetate (PMA), and lipopolysaccharide (LPS) induce OSM expression. To investigate the mechanisms governing OSM promoter activity, we have cloned and partially
A Grenier et al.
Blood, 93(4), 1413-1421 (1999-02-09)
Oncostatin M (OSM) is an interleukin-6 (IL-6) family cytokine known in particular to induce the synthesis of acute-phase proteins by hepatocytes. Because human polymorphonuclear neutrophils (PMN) can secrete numerous cytokines, the potential production of OSM by PMN was investigated. Highly
Pulmonary expression of oncostatin M (OSM) promotes inducible BALT formation independently of IL-6, despite a role for IL-6 in OSM-driven pulmonary inflammation.
Botelho FM
Journal of Immunology, 191, 1453-1464 (2013)

Related Content

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service