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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... PGF(5228)
Input:
sample type urine
sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type cell culture supernatant(s)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type urine
sample type serum
sample type plasma
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 1.372-1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... PGF(5228)
General description
The Human PGF (placenta growth factor) ELISA (Enzyme- Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human PGF in serum, plasma, cell culture supernatants and urine.
The PGF (placental growth factor) gene codes for a proangiogenic factor and is mapped to human chromosome 14q24.3. PGF belongs to the vascular endothelial growth factor (VEGF) family of growth factors. It is predominantly expressed in placenta.
The PGF (placental growth factor) gene codes for a proangiogenic factor and is mapped to human chromosome 14q24.3. PGF belongs to the vascular endothelial growth factor (VEGF) family of growth factors. It is predominantly expressed in placenta.
Immunogen
Recombinant Human PLGF
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human Placental Growth Factor ELISA Kit has been used to determine PGF in the medium culture waste and cellular suspension.
Human Placental Growth Factor ELISA Kit has been used to determine PGF in the medium culture waste and cellular suspension.
Biochem/physiol Actions
Reduced levels of placental growth factor (PGF) indicates restricted growth in the fetus. Increased stimulation of PGF is observed in cancers and hind limb ischemia and in wound healing. Hypoxic conditions upregulate PGF expression. Increased expression of PGF gene is observed in cutaneous T-cell lymphoma and it supports in the cell proliferation process.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
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Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8B - Non-combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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The discovery of the placental growth factor and its role in angiogenesis: a historical review.
Ribatti D
Angiogenesis, 11(3), 215-221 (2008)
Placental growth factor and vascular endothelial growth factor together regulate tumour progression via increased vasculature in cutaneous T-cell lymphoma.
Miyagaki T, et al.
Acta Dermato-Venereologica, 97(5), 586-592 (2017)
Akiyo Sekimoto et al.
Biochemical and biophysical research communications, 521(3), 769-774 (2019-11-11)
- Tadalafil, a long-acting phosphodiesterase 5 (PDE5) inhibitor, alleviates preeclampsia (PE), and decreases the fetal and infant deaths associated with fetal growth restriction (FGR) in phase II clinical trial. Recently, we demonstrated that tadalafil alleviates FGR and hypertension in the
Sophida Phuthong et al.
International journal of molecular sciences, 22(1) (2021-01-01)
Fetal undernutrition programs cardiometabolic diseases, with higher susceptibility in males. The mechanisms implicated are not fully understood and may be related to sex differences in placental adaptation. To evaluate this hypothesis, we investigated placental oxidative balance, vascularization, glucocorticoid barrier, and
Modulation of cerebral endothelial cell function by TGF-? in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition.
Krishnan S, et al.
Oncotarget, 6(26), 22480-22480 (2015)
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