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Merck
CN

RAB0607

Human APOA1 / Apolipoprotein A-I ELISA Kit

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.08 ng/mL
standard curve range: 0.082-20 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... APOA1(335)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

General description

Apolipoprotein A-1 (APOA1) is a major constituent of high-density lipoprotein (HDL) cholesterol. It aids in reverse cholesterol transport (RCT). In addition, apoA1 is also implicated in the pathways that protect endothelial functions, induce nitric oxide-mediated vasodilatation, and reduce vascular cell adhesion molecule-1 (VCAM-I) expression. APOA1 stimulates proliferation by inhibiting apoptosis. The ApoA enzyme-linked immunosorbent assay (ELISA) kit provides for the quantitative measurement of ApoA1 in cell culture supernatants, plasma, and serum.
The ApoA ELISA kit provides for the Quantitative measurement of ApoA1 in Cell Culture Supernatants, Plasma and Serum.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Manja Koch et al.
Journal of lipid research, 58(6), 1196-1203 (2017-04-04)
The presence of apoC-III on HDL impairs HDL's inverse association with coronary heart disease (CHD). Little is known about modifiable factors explaining variation in HDL subspecies defined according to apoC-III. The aim was to investigate cross-sectional associations of anthropometry and
Thomas Lundåsen et al.
PloS one, 15(3), e0229322-e0229322 (2020-03-17)
Tetradecylthioacetic acid (TTA) is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including activation of peroxisome proliferator activated receptors (PPARs) with preference for
Michael A Tortorici et al.
Clinical pharmacology in drug development, 8(5), 628-636 (2018-09-22)
CSL112 (Apolipoprotein A-I [human]) is an intravenous preparation of apolipoprotein A-I (apoA-I), formulated with phosphatidylcholine (PC) and stabilized with sucrose, in development to prevent early recurrent cardiovascular events following acute myocardial infarction (AMI). This phase 1 study was designed to
Jolanta Parada-Turska et al.
Antioxidants (Basel, Switzerland), 9(9) (2020-09-25)
Paraoxonase 1 (PON1) is the high density lipoprotein-associated esterase which inhibits the development of atherosclerosis by metabolizing lipid peroxidation products as well as hydrolyzing proatherogenic metabolite of homocysteine (Hcy), Hcy thiolactone, which otherwise reacts with lysine groups of proteins, thus
Priyanka Verma et al.
Reproductive sciences (Thousand Oaks, Calif.), 26(5), 649-656 (2018-07-14)
Early miscarriage (EM) is one of the most devastating obstetrical complications globally affecting the quality of women's life. In the present study, we aimed to identify proteins that correlate with and could act as biomarkers for EM. We performed 2-dimensional

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