Skip to Content
Merck
CN

RAB0634

Human TNNI3 / Troponin I, Cardiac Muscle ELISA Kit

Sign In to View Organizational & Contract Pricing.

Select a Size


About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 100 pg/mL
standard curve range: 125-8000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TNNI3(7137)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

It is found to be implicated in dilated cardiomyopathy, indicating left ventricle dilation and decreased systolic function. cTnI along with cardiac troponin T and C, forms the troponin complex. cTnI prevents actin-myosin interaction. It participates in sarcomere activation by influencing Ca2+ sensitivity. cTnI also serves as a myocardial injury marker.

General description

The TNNI3 ELISA kit provides for the Quantitative measurement of Troponin I in Cell Culture Supernatants, Plasma and Serum.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Sandra Funcke et al.
Biomolecules, 10(9) (2020-09-17)
Intermittent hypoxia and various pharmacological compounds protect the heart from ischemia reperfusion injury in experimental approaches, but the translation into clinical trials has largely failed. One reason may lie in species differences and the lack of suitable human in vitro
Hongrui Chen et al.
Life sciences, 207, 492-498 (2018-07-03)
The clinical use of doxorubicin (Dox) is limited due to a degenerative irreversible cardiac toxicity, but the precise mechanisms that contribute to this pathological response are not understood. C1q/TNF-related protein 1 (CTRP1), which is a conserved protein of the C1q
Junjie Guo et al.
Shock (Augusta, Ga.), 49(6), 712-720 (2017-08-29)
Chronic kidney disease (CKD) is known to exacerbate myocardial ischemia reperfusion (IR) injury. However, the underlying mechanisms are still not well understood. Despite various strategies for cardioprotection, limited studies have been focused on the prevention of CKD-induced myocardial susceptibility to
Correlation of corrected QT interval with quantitative cardiac troponin-I levels and its prognostic role in Non-ST-elevation myocardial infarction
Rajvanshi S, et al.
International Journal of Cardiology, 240(14), 55-59 (2017)
Genotype-specific pathogenic effects in human dilated cardiomyopathy
Bollen IA, et al.
The Journal of Physiology, 595(14), 4677-4693 (2017)

Related Content

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service