RAB0657
Human FABP3 / Fatty Acid-binding Protein, Heart ELISA Kit
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.5 ng/mL
standard curve range: 2.05-200 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... FABP3(2170)
Application
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Fatty acid-binding protein-3 (FABP3) participates in cardiac metabolism. It plays an important role in the intracellular uptake of fatty acids and their migration towards the mitochondrial β-oxidation system.
General description
Fatty acid-binding protein-3 (FABP3) is a small cytoplasmic protein, which is a member of the multigene family of FA-binding proteins. It is widely expressed in the heart. This gene is mapped to human chromosome 1p35.
SRC family belongs to non-receptor tyrosine kinases. SRC was originally identified as a transforming protein of the Rous sarcoma virus (RSV) that had enzymatic ability to phosphorylate tyrosine in protein substrates. SRC is overexpressed and activated in a large number of human malignancies and has been linked to the development of cancer and progression to distant metastases. In addition to increasing cell proliferation, a key role of SRC in cancer seems to be the ability to promote invasion and motility, functions that might contribute to tumour progression
Other Notes
A sample Certificate of Analysis is available for this product.
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Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Aml Gaber Mohammed Mohammed et al.
Iranian journal of kidney diseases, 13(2), 120-128 (2019-04-17)
Myocardial dysfunction is a leading cause of mortality in chronic kidney disease (CKD) children specially those on regular hemodialysis. Cardiac biomarkers play a key role for early detection of myocardial injury. We aim to clarify the prognostic role of circulating
Claire J C Huguenard et al.
Frontiers in physiology, 11, 12-12 (2020-02-23)
The differential diagnosis between mild Traumatic Brain Injury (mTBI) sequelae and Post-Traumatic Stress Disorder (PTSD) is challenging due to their symptomatic overlap and co-morbidity. As such, there is a need to develop biomarkers which can help with differential diagnosis of
Louis Servaas Dolmans et al.
BMJ open, 9(10), e031774-e031774 (2019-10-20)
The diagnosis of transient ischaemic attack (TIA) based on symptoms and signs can be challenging and would greatly benefit from a rapid serum biomarker of brain ischaemia. We aimed to quantify the added diagnostic value of serum biomarkers in patients
The circulating level of FABP3 is an indirect biomarker of microRNA-1
Varrone F, et al.
Journal of the American College of Cardiology, 61(1), 88-95 (2013)
Rafał Mikołajczyk et al.
Journal of human kinetics, 71, 155-166 (2020-03-10)
The aim of this study was to assess the effects of incremental and continuous exercise on the concentration of insulin-like growth factor-1 (IGF-1), growth hormone (GH), testosterone (T), and cortisol (C), as well as to investigate whether increased cardiac dimensions
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