RAB0720
Human PAPPA / Pappalysin-1 ELISA Kit
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... PAPPA(5069)
Input:
sample type plasma
sample type cell culture supernatant(s)
sample type serum
sample type cell culture supernatant(s)
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.6 ng/mL
standard curve range: 0.686-500 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... PAPPA(5069)
General description
The PAPPA ELISA kit provides for the Quantitative measurement of Pappalysin-1 in Cell Culture Supernatants, Plasma and Serum.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Erik Nilsson et al.
European journal of clinical investigation, 48(8), e12959-e12959 (2018-05-29)
Elevated pregnancy-associated plasma protein A (PAPP-A) levels are associated with increased risk of death in ischaemic heart disease as well as in haemodialysis patients. Previous research indicates that the prognostic value of PAPP-A may be stronger in patients with concomitant
Dursun Ali Sirin et al.
Odontology, 109(1), 250-258 (2020-07-01)
To examine the use of IL-6 and PAPP-A along with the new imaging for scoring methods to determine the severity of apical periodontitis (AP). The scoring of disease severity in 121 patients with AP, using dental radiographs, was based on
Sonu Kashyap et al.
JCI insight, 5(4) (2020-01-29)
Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic cause of end-stage renal disease (ESRD). The treatment options for ADPKD are limited. We observed an upregulation in several IGF-1 pathway genes in the kidney of Pkd1RC/RC mice, a
Lucio Barile et al.
Cardiovascular research, 114(7), 992-1005 (2018-03-09)
Cell therapy trials using cardiac-resident progenitor cells (CPCs) and bone marrow-derived mesenchymal stem/progenitor cells (BMCs) in patients after myocardial infarction have provided encouraging results. Exosomes, nanosized extracellular vesicles of endosomal origin, figure prominently in the bioactivities of these cells. However
Overcoming platinum resistance in ovarian cancer by targeting pregnancy-associated plasma protein-A.
Diogo Torres et al.
PloS one, 14(11), e0224564-e0224564 (2019-11-22)
Inhibition of pregnancy-associated plasma protein-A (PAPP-A), an upstream activator of the insulin-like growth factor (IGF) pathway, is known to augment sensitivity to platinum-based chemotherapy. This study further tests the efficacy of PAPP-A inhibition with a monoclonal antibody inhibitor (mAb-PA) in
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