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Merck
CN

RAB0871

Porcine IL18 / Interleukin-18 ELISA Kit

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
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species reactivity

porcine

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 81.92-20000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

Porcine ... IL18(397057)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Interleukin-18 along with IL-12, induces the production of interferon gamma. It participates in the modulation of lipid and glucose metabolism. It plays a major role in inflammation. Overexpression of IL-18 result in inflammatory diseases such as inflammatory myopathies and COPD (chronic obstructive pulmonary disease).

General description

Porcine IL18 / interleukin-18 is a cofactor that belongs to the IL-1 family. It is expressed in many mammalian cells/tissues like liver, adipose tissue and skeletal muscle. This gene is located on human chromosome 11q23.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Low expression of IL-18 and IL-18 receptor in human skeletal muscle is associated with systemic and intramuscular lipid metabolism?Role of HIV lipodystrophy.
Lindegaard B, et al.
PLoS ONE, 13(1), e0186755-e0186755 (2018)
Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study.
Brophy K, et al.
BMC Medical Genetics, 11(1), 76-76 (2010)

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